Intravenous Detoxification with Glutathione

Dr. Ariel Mastrich, ND

Glutathione, a tri-peptide amino acid made within the cells of the body, is a major antioxidant. It is a free radical scavenger and an essential component of liver detoxification. It is an unusual amino acid because it can do two jobs to protect our bodies from toxins. First, it neutralizes free radicals in our body, such as toxic compounds from Phase I detoxification. Second, it combines with Phase II toxic chemicals to form water-soluble compounds, which allows for easier excretion into the bile & urine.

Besides protecting cells against the destructive effects of free radicals and detoxifying substances, such as drugs and environmental pollutants, it also helps maintain cell membrane stability. Glutathione regulates protein and DNA biosynthesis, cell growth and it enhances immune system function through its effects on lymphocytes, which respond to viral infections.

Glutathione depletion has been linked with biologic aging, first noted in the lens of the eye. Today, all eye diseases are linked to depleted levels of glutathione. The widespread functions of glutathione indicate that the level of glutathione in one's body has the major health effects on the molecular, cellular, and organ levels of the individual. People who maintain high levels of glutathione represent survivors with extreme longevity.

Glutathione is a very powerful antioxidant, however oral supplementation of glutathione does not increase body stores because it does not cross the intestinal barrier. To significantly increase glutathione in the bloodstream, intravenous application is necessary. Glutathione can be consumed in the form of fresh fruits and vegetables, but concentrated doses may be achieved intravenously.

Aging & Glutathione
Higher glutathione levels in individuals over 60 were associated with fewer illness and higher levels of self-rated health, lower cholesterol, and lower blood pressure. Those with diagnoses of arthritis, diabetes or heart disease had marginally to significant lower glutathione levels than those who were disease-free.

Cancer & Glutathione
Glutathione therapy can reduce the toxicity of some chemotherapeutic agents. Glutathione is a safe compound that prevents Cisplatin-induces kidney toxicity without affecting its anti-tumor activity. Treatment including glutathione in any adjunct cancer treatment will increase efficacy against tumor cells and increase survivorship and longevity.

HIV/AIDS & Glutathione
Patients with HIV & AIDS have low glutathione levels. Oral supplementation of precursors of glutathione can inhibit HIV replication and may do so by replenishing intracellular glutathione. An addition of high dose Vitamin C along with IV glutathione may reduce glutathione to its active form and slows the reduction of CD4 T-cells, reduced allergic reactions to antibiotics, reduction in lymphadenopathy and improvement in fatigue and malaise.

Other conditions that warrant glutathione intravenously include people with severe toxicity (Heavy Metal Toxicity, Cancer), central nervous system damage (Parkinson' Disease, Dementia, Alzheimer's Disease, Multiple Sclerosis) hepatic disease (Hepatitis), chronic viral disease (HIV/AIDS, Lyme Disease), autoimmune diseases (Rheumatoid Arthritis, Lupus, Sjogren's Syndrome), renal disease, and general detoxification & wellness.

For more information regarding IV Glutathione therapy, please contact our front desk or email Dr. Ariel Mastrich at with any questions.